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Carbetocin

  • CAS No.: 37025-55-1
  • Purity: 99%
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1.What is the (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT ?

Carbetocin is an obstetric drug used to control postpartum hemorrhaging.A new synthetic analog of oxytocin, carbetocin, is long acting and also has a rapid onset of action. It is an oxytocin receptor agonist and also stimulates milk let down due to its action on oxytocin receptors of myoepithelial cells.

C<sub>45</sub>H<sub>71</sub>N<sub>11</sub>O<sub>13</sub>S*C<sub>2</sub>HF<sub>3</sub>O<sub>2</sub>

C45 H71 N11 O13 S*C2 HF3 O2

Carbetocin
37025-55-1

Carbetocin

Conditions
Conditions Yield
With 4-methyl-morpholine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; In N,N-dimethyl-formamide; at 0 - 30 ℃; for 3h;
N-(fluoren-9-ylmethoxycarbonyl)glycine
29022-11-5

N-(fluoren-9-ylmethoxycarbonyl)glycine

Fmoc-Leu-OH
35661-60-0

Fmoc-Leu-OH

Fmoc-Pro-OH
71989-31-6

Fmoc-Pro-OH

Fmoc-Ile-OH
71989-23-6,251316-98-0

Fmoc-Ile-OH

L-Asn(Trt)
132388-59-1

L-Asn(Trt)

Fmoc-L-Gln(Trt)-OH
132327-80-1,200623-62-7

Fmoc-L-Gln(Trt)-OH

4-[(2R)-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethylsulfanyl]butyric acid tert butyl ester
102971-73-3

4-[(2R)-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethylsulfanyl]butyric acid tert butyl ester

N-(9-fluorenylmethoxycarbonyl)-O-methyl-L-tyrosine
77128-72-4,201335-88-8

N-(9-fluorenylmethoxycarbonyl)-O-methyl-L-tyrosine

Carbetocin
37025-55-1

Carbetocin

Conditions
Conditions Yield
N-(fluoren-9-ylmethoxycarbonyl)glycine; With benzotriazol-1-ol; diisopropyl-carbodiimide; In N,N-dimethyl-formamide;
With piperidine; In N,N-dimethyl-formamide;
Fmoc-Leu-OH; Fmoc-Pro-OH; Fmoc-Ile-OH; L-Asn(Trt); Fmoc-L-Gln(Trt)-OH; 4-[(2R)-carboxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)ethylsulfanyl]butyric acid tert butyl ester; N-(9-fluorenylmethoxycarbonyl)-O-methyl-L-tyrosine; Further stages;

2.What is the CAS number for (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT ?

The CAS number of (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT is 37025-55-1.

More information of (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT 37025-55-1 are:

CAS?Number

37025-55-1

Density

1.218 g/cm3

Boiling Point

1477.9 °C at 760 mmHg

Flash Point

847.6 °C

Vapor Pressure

0mmHg at 25°C

Refractive Index

1.541

PSA

387.81000

LogP

1.96370

Pka

13.07±0.70(Predicted)

3.What are another words for (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT ?

Synonyms?for?(BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT 37025-55-1:Deamino-2-O-methyltyrosine-1-carbaoxytocin;[2-O-Methyltyrosine]-deamino-1-carba-oxytocin;

4.What is the molecular formula of (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT?

The chemical formula of ?(BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT is?C45 H69 N11 O12 S which containing 45 Carbon atoms,69 Hydrogen atoms,11 Nitrogen atoms,12 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??(BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT?is 988.175.

5.What is (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT (37025-55-1) used for?

Carbetocin is an alternative synthetic oxytocin-receptor agonist available in Canada, the United Kingdom, and other countries,but not the United States. A large multinational randomized noninferiority trial (N=29,645) found that carbetocin was noninferior to oxytocin for prevention of postpartum hemorrhage and need for additional uterotonic agents after vaginal delivery. Carbetocin has a longer duration of action than oxytocin, eliminating the need for prolonged infusion.

InChI:InChI=1/C45H69N11O12S/c1-6-25(4)38-44(67)50-28(15-16-34(46)58)40(63)51-30(21-35(47)59)41(64)53-31(23-69-18-8-10-37(61)55(5)33(43(66)54-38)20-26-11-13-27(57)14-12-26)45(68)56-17-7-9-32(56)42(65)52-29(19-24(2)3)39(62)49-22-36(48)60/h11-14,24-25,28-33,38,57H,6-10,15-23H2,1-5H3,(H2,46,58)(H2,47,59)(H2,48,60)(H,49,62)(H,50,67)(H,51,63)(H,52,65)(H,53,64)(H,54,66)/t25-,28-,29-,30-,31-,32-,33-,38-/m0/s1

Relevant articles related to (BUTYRYL1,TYR(ME)2)-1-CARBAOXYTOCIN TRIFLUOROACETATE SALT:

Article

Source

New, potent, and selective peptidic oxytocin receptor agonists

Wi?niewski, Kazimierz,Alagarsamy, Sudarkodi,Galyean, Robert,Tariga, Hiroe,Thompson, Dorain,Ly, Brian,Wi?niewska, Halina,Qi, Steve,Croston, Glenn,Laporte, Regent,Rivière, Pierre J.-M.,Schteingart, Claudio D.

supporting information, p. 5306 - 5317 (2014/07/08)

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