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Octreotide Acetate

  • CAS No.:83150-76-9
  • Purity:99%
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Reputable factory supply Octreotide Acetate 83150-76-9 in stock with high standard We provide high quality Octreotide acetate (CAS 83150-76-9), at a very affordable prices to our customers.

1.What is the Octreotide acetate ?

Octreotide is a long-acting somatostatin analog indicated for symptomatic control in acromegaly and gastroenteropancreatic tumors. Other potential uses under investigation include diabetes, psoriasis and Alzheimer's disease.

Octreotide acetate (Sandostatin) is a synthetic peptide analogue of the hormone somatostatin. Its actions include inhibition of the pituitary secretion of growth hormone and an inhibition of pancreatic islet cell secretion of insulin and glucagon. Unlike somatostatin, which has a plasma half-life of a few minutes, octreotide has a plasma elimination half-life of 1 to 2 hours. Excretion of the drug is primarily renal.

Octreotide Acetate is the acetate salt of a synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. It inhibits the secretion of growth hormone, glucagon, insulin, gastrin, vasoactive intestinal peptide, secretin, motilin and pancreatic polypeptide. Octreotide acetate was uses for the treatment of severe diarrhea and flushing associated with malignant carcinoid tumors, acromegaly, and diarrhea associated with VIPoma; and, then in 2010, for the treatment of neuroendocrine tumors.

2.What is the CAS number for Octreotide acetate ?

The CAS number of Octreotide acetate is 83150-76-9.

More information of Octreotide acetate 83150-76-9 are:

CAS?Number

83150-76-9

Density

1.395 g/cm3

Boiling Point

1447.228°C at 760 mmHg

Flash Point

829.053 C

Vapor Pressure

0mmHg at 25°C

Refractive Index

1.673

HS CODE

3004909090

PSA

382.82000

LogP

3.02100

Pka

12.60±0.70(Predicted)

3.What is the molecular formula of Octreotide acetate ?

The chemical formula of?Octreotide acetate is C49H66N10O10S2 which containing 49 Carbon atoms,66 Hydrogen atoms,10 Nitrogen atoms,10 Oxygen atoms and 2 Sulfur atoms,and the molecular weight, and the molecular weight of Octreotide acetate is 1019.26

4.What is Octreotide acetate(83150-76-9)used for?

Octreotide is a long-acting somatostatin analog indicated for symptomatic control in acromegaly and gastroenteropancreatic tumors. Other potential uses under investigation include diabetes, psoriasis and Alzheimer's disease.

InChI:InChI=1/C49H66N10O10S2.C2H4O2/c1-28(61)39(25-60)56-48(68)41-27-71-70-26-40(57-43(63)34(51)21-30-13-5-3-6-14-30)47(67)54-37(22-31-15-7-4-8-16-31)45(65)55-38(23-32-24-52-35-18-10-9-17-33(32)35)46(66)53-36(19-11-12-20-50)44(64)59-42(29(2)62)49(69)58-41;1-2(3)4/h3-10,13-18,24,28-29,34,36-42,52,60-62H,11-12,19-23,25-27,50-51H2,1-2H3,(H,53,66)(H,54,67)(H,55,65)(H,56,68)(H,57,63)(H,58,69)(H,59,64);1H3,(H,3,4)/t28-,29-,34-,36+,37+,38-,39-,40+,41+,42+;/m1./s1

Relevant articles related to Octreotide acetate:

Article

Source

Use of trichloroacetimidate linker in solid-phase peptide synthesis

Yan, Liang Zeng,Mayer, John P.

, p. 1161 - 1162 (2003)

Electrophilic S-trifluoromethylation of cysteine side chains in α- and β-peptides: Isolation of trifluoromethylated sandostatin (octreotide) derivatives

Caponea, Stefania,Kieltschb, Iris,Floegela, Oliver,Lelaisa, Gerald,Togni, Antonio,Seebach, Dieter

body text, p. 2035 - 2056 (2009/02/08)

5.Reputable factory supply Octreotide Acetate 83150-76-9 in stock with high standard

Suzhou Sinhico Chemical Company Limited is a quality supplier of Octreotide acetate. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Octreotide acetate 83150-76-9.

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